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> Home > Eventi a Torino del 14-10-2019 > Mostre e Cultura > Empowering the Immune System to Fight Against...

Empowering the Immune System to Fight Against Cancer

Empowering the Immune System to Fight Against Cancer



Conferenza in lingua inglese a cura di Giovanni Germano PhD Ricercatore dell' Università degli Studi di Torino Fondazione del Piemonte per l'Oncologia - Istituto di Candiolo - IRCCS INGRESSO LIBERO It is well known that to grow and invade different organs, tumours must find ways to evade several layers of controls that are in place in our body. The immune system, a complex network of cells and antibodies has been shaped by evolution to protect us, not only against virus and bacterial infections but also against cancer. Different players of the immune system cooperate at different times, and multiple mechanisms are involved in cancer control. For instance, several hundred billion of specific cells (T cells) reside in lymphoid tissues and in the bloodstream to detect and destroy viruses, bacteria, and cancer cells. Unfortunately, cancers are able to escape the immune control. By-the-way, do not be confused by the overused and misleading anthropomorphism in sentences like “cancer must find a way” or “cancers are able to”. Cancers have no brain, no plan, no free will; they bear neither virtue nor malice. Cancer cells are automatons that act because of corrupted software, not an evil purpose. Indeed, cancers become able to evade immune controls thanks to intrinsic genetic instability: they undergo Darwinian-like evolution in months-years rather than over the eons. The immune system is an arduous enemy for the survival but tumors continuously and rapidly evolve selecting for “species” (cancer clones) that best fit in the environment, blending in or blocking the immune mechanisms. The last 50 years have seen a therapeutic revolution and now any approach that aims to spark cancer immunity - also called immunotherapy - is potentially relevant for increasing the survival rate of cancer patients. The strategies are multiple, and all are oriented towards the formation of an immune-reactive environment. Immunotherapy has been initially seen as a “one-size-fits-all” modality, because the immune system is healthy and governed by the same rules in all patients. However, despite some striking results obtained, complete tumour remission is rare and has not been described for a wide range of tumour types. Indeed, the number of patients that receive benefits remains low, and new findings are needed to combine the different faces of the immunological medal.

Dati Aggiornati al: 09-10-2019 19:12:12 non è l'organizzatore dell'evento e non è responsabile di eventuali cambiamenti di programma.

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Categoria: Mostre e Cultura

Quando: Lunedì 14-10-2019 alle 18:30

Dove: Collegio Universitario di Torino "Renato Einaudi"

Indirizzo: Via Maria Vittoria, 39 Torino

Prezzo: Gratis

Link: Sito Web dell'evento